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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFKP
All Species:
4.73
Human Site:
S6
Identified Species:
8.68
UniProt:
Q01813
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01813
NP_002618.1
784
85596
S6
_
_
M
D
A
D
D
S
R
A
P
K
G
S
L
Chimpanzee
Pan troglodytes
XP_507625
746
81795
R6
_
_
M
N
A
A
V
R
A
V
V
R
M
G
I
Rhesus Macaque
Macaca mulatta
XP_001118490
717
78539
Dog
Lupus familis
XP_535201
901
98160
S85
W
R
I
S
K
S
E
S
Y
A
V
N
A
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUA3
784
85437
S9
S
D
L
D
S
S
S
S
S
A
Y
P
K
Y
L
Rat
Rattus norvegicus
P47860
788
85702
S6
_
_
M
S
D
Q
D
S
S
T
S
S
T
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511162
864
94802
E73
I
A
V
L
A
D
R
E
Q
T
V
S
G
T
K
Chicken
Gallus gallus
NP_989554
769
83907
A6
_
_
M
G
A
G
K
A
I
A
V
L
T
S
G
Frog
Xenopus laevis
NP_001091319
786
86623
L8
M
A
Q
P
D
K
R
L
F
E
N
L
S
G
K
Zebra Danio
Brachydanio rerio
XP_002666643
787
86261
N6
_
_
M
A
Q
S
D
N
K
R
F
F
E
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52034
788
86630
N6
_
_
M
N
S
E
I
N
Q
R
F
L
A
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27483
756
83282
K6
_
_
M
E
Q
K
F
K
K
G
K
D
H
G
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P16862
959
104599
R178
S
Y
T
D
L
A
Y
R
M
K
T
T
D
T
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
89.4
78.9
N.A.
88.5
87.9
N.A.
77.1
70.7
81.3
79.6
N.A.
58.8
N.A.
40.6
N.A.
Protein Similarity:
100
95
90.4
83.5
N.A.
93.6
93.4
N.A.
84.1
82
90.5
89.3
N.A.
75.8
N.A.
59.6
N.A.
P-Site Identity:
100
15.3
0
13.3
N.A.
26.6
30.7
N.A.
20
30.7
0
23
N.A.
7.6
N.A.
7.6
N.A.
P-Site Similarity:
100
38.4
0
33.3
N.A.
40
30.7
N.A.
46.6
38.4
0
46.1
N.A.
46.1
N.A.
30.7
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
8
31
16
0
8
8
31
0
0
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
24
16
16
24
0
0
0
0
8
8
0
0
% D
% Glu:
0
0
0
8
0
8
8
8
0
8
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
8
0
16
8
0
0
16
% F
% Gly:
0
0
0
8
0
8
0
0
0
8
0
0
16
24
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
8
0
0
0
8
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
8
16
8
8
16
8
8
8
8
0
16
% K
% Leu:
0
0
8
8
8
0
0
8
0
0
0
24
0
0
24
% L
% Met:
8
0
54
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
0
0
16
0
0
0
16
0
0
8
8
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
8
0
16
8
0
0
16
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
16
16
8
16
0
8
0
8
0
% R
% Ser:
16
0
0
16
16
24
8
31
16
0
8
16
8
24
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
16
8
8
16
16
0
% T
% Val:
0
0
8
0
0
0
8
0
0
8
31
0
0
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
8
0
8
0
0
8
8
% Y
% Spaces:
54
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% _